Began playing tennis at age 9. Also played basketball until age 14.
Wife, Madison; daughter, Hunter Grace; sons, John Hobbs and James McKinley; father, Robert; mother, Karen; brothers, Jordan and Nathan.
Four-year All-American at University of Georgia (2004-07), winning 2005 NCAA doubles title w/Ruiz, reaching 2007 NCAA singles final and leading Bulldogs to 2007 NCAA team title.
Voted ATP Most Improved Player of the Year in 2009.
Member of ATP Player Council for 3 terms from 2014-20.
Enjoys playing poker, golf, basketball and fishing.
Fan of Carolina Panthers (NFL) and Carolina Hurricanes (NHL).
Launched Isner Family Foundation in 2019 to fundraise for Dallas hospitals. Also supports UNC Lineberger Comprehensive Cancer Center, where his mom was successfully treated twice.
Partners with Nulo Pet Food on "Aces for Animals" campaign.
Donated $53,500 to Australian bushfire relief in January 2020.
Missed 3 months in 2019 due to foot injury.
(UPDATED 21 AUGUST2023)
Finished in Top 20 for 10 consecutive years from 2010-2019 with year-end best No. 10 in 2018 and overall 14 straight seasons in Top 50 from 2009-22. Finished as No. 1 American for 8 years (2012-16, 2018-2020).Heachieved career-high No. 8 in July 2018after reaching 1st Grand Slam SF atWimbledon (l. to Anderson 26-24 in 5th after 6:36). Won personal-best 45 matches in 2012 and 2015.Dropped out of Top 50 on 10 April 2023 at No. 68 for 1st time since 7 September 2009.
Owns 16 ATP Tour titles, including 6 at Atlanta, 4 at Newport and 2 at Winston-Salem (all tournament records).
Became oldest 1st-time ATP Masters 1000 singles champion as 32-year-old at 2018 Miami (d. Zverev) and owns 5 ATP Masters 1000 doubles titles.
Servedan ATP record 14,411aces in ATP Tour and Grand Slam singles matches (since ATP records have been kept back to1991), including record 113 to win longest match on record over Mahut in 2010 Wimbledon 1R (70-68 in 5th after 11:05 across 3 days).
Won 5 straight 3rd-set TBs for 1st career victories at 2007 Washington and counts wins over No. 1 Djokovic, No. 1 Nadal and No. 2 Federer among his 488career victories.
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